As the U.S. COVID death toll tops 450,000, the Biden administration is attempting to ramp up its vaccination campaign to slow the spread of new coronavirus variants. Meanwhile, health experts warn any vaccination progress in the United States will be threatened without global vaccine equity. “We need to, as quickly as possible, expand access to the vaccines, both in this country, in the United States, as well as around the world,” says Dr. Wafaa El-Sadr, director of the ICAP at Columbia University and professor of epidemiology and medicine at the Columbia Mailman School of Public Health. She argues that the U.S. needs to do more to supply the world with COVID-19 vaccines, as it did with HIV medications. “This is a model that can be emulated at this point in time in recognition of the fact that viruses know no borders.”